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SeqVerify: An accessible analysis tool for cell line genomic integrity, contamination, and gene editing outcomes

1. Over the last decade, advances in genome editing and pluripotent stem cell (PSC) culture have let researchers generate edited PSC lines to study a wide variety of biological questions. However, abnormalities in cell lines such as aneuploidy, on-target and off-target editing errors, and microbial...

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Detalles Bibliográficos
Autores principales: Smela, Merrick Pierson, Pepe, Valerio, Church, George M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565884/
https://www.ncbi.nlm.nih.gov/pubmed/37829615
http://dx.doi.org/10.1101/2023.09.27.559766