Hypoxia-induced SKA3 promoted cholangiocarcinoma progression and chemoresistance by enhancing fatty acid synthesis via the regulation of PAR-dependent HIF-1a deubiquitylation

BACKGROUND: Spindle and kinetochore-associated complex subunit 3 (SKA3) plays an important role in cell proliferation by regulating the separation of chromosomes and their division into daughter cells. Previous studies demonstrated that SKA3 was strongly implicated in tumor development and progressi...

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Detalles Bibliográficos
Autores principales: Chen, Yananlan, Xu, Xiao, Wang, Yirui, Zhang, Yaodong, Zhou, Tao, Jiang, Wangjie, Wang, Ziyi, Chang, Jiang, Liu, Shuochen, Chen, Ruixiang, Shan, Jijun, Wang, Jifei, Wang, Yuming, Li, Changxian, Li, Xiangcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565972/
https://www.ncbi.nlm.nih.gov/pubmed/37821935
http://dx.doi.org/10.1186/s13046-023-02842-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565972/
https://www.ncbi.nlm.nih.gov/pubmed/37821935
http://dx.doi.org/10.1186/s13046-023-02842-7

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