Nanobody-based pannexin1 channel inhibitors reduce inflammation in acute liver injury

BACKGROUND: The opening of pannexin1 channels is considered as a key event in inflammation. Pannexin1 channel-mediated release of adenosine triphosphate triggers inflammasome signaling and activation of immune cells. By doing so, pannexin1 channels play an important role in several inflammatory dise...

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Detalles Bibliográficos
Autores principales: Van Campenhout, Raf, De Groof, Timo W. M., Kadam, Prashant, Kwak, Brenda R., Muyldermans, Serge, Devoogdt, Nick, Vinken, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566086/
https://www.ncbi.nlm.nih.gov/pubmed/37821897
http://dx.doi.org/10.1186/s12951-023-02137-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566086/
https://www.ncbi.nlm.nih.gov/pubmed/37821897
http://dx.doi.org/10.1186/s12951-023-02137-1

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