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Nanobody-based pannexin1 channel inhibitors reduce inflammation in acute liver injury
BACKGROUND: The opening of pannexin1 channels is considered as a key event in inflammation. Pannexin1 channel-mediated release of adenosine triphosphate triggers inflammasome signaling and activation of immune cells. By doing so, pannexin1 channels play an important role in several inflammatory dise...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566086/ https://www.ncbi.nlm.nih.gov/pubmed/37821897 http://dx.doi.org/10.1186/s12951-023-02137-1 |