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Beyond the G protein α subunit: investigating the functional impact of other components of the Gαi(3) heterotrimers

BACKGROUND: Specific interactions between G protein-coupled receptors (GPCRs) and G proteins play a key role in mediating signaling events. While there is little doubt regarding receptor preference for Gα subunits, the preferences for specific Gβ and Gγ subunits and the effects of different Gβγ dime...

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Detalles Bibliográficos
Autores principales: Rysiewicz, Beata, Błasiak, Ewa, Mystek, Paweł, Dziedzicka-Wasylewska, Marta, Polit, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566112/
https://www.ncbi.nlm.nih.gov/pubmed/37817242
http://dx.doi.org/10.1186/s12964-023-01307-w