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GFAP-NpHR mediated optogenetic inhibition of trigeminal nucleus caudalis attenuates hypersensitive behaviors and thalamic discharge attributed to infraorbital nerve constriction injury

The significance of hyperactive astrocytes in neuropathic pain is crucial. However, the association between medullary astrocytes and trigeminal neuralgia (TN)-related pain processing is unclear. Here, we examined how optogenetic inhibition of medullary astrocytes in the trigeminal nucleus caudalis (...

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Detalles Bibliográficos
Autores principales: KC, Elina, Islam, Jaisan, Kim, Hyong Kyu, Park, Young Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566148/
https://www.ncbi.nlm.nih.gov/pubmed/37821818
http://dx.doi.org/10.1186/s10194-023-01669-z