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Readthrough isoform of aquaporin-4 (AQP4) as a therapeutic target for Alzheimer’s disease and other proteinopathies

The glymphatic system is a crucial component in preserving brain homeostasis by facilitating waste clearance from the central nervous system (CNS). Aquaporin-4 (AQP4) water channels facilitate the continuous interchange between cerebrospinal fluid and brain interstitial fluid by convective flow move...

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Detalles Bibliográficos
Autores principales: Mohaupt, Pablo, Vialaret, Jérôme, Hirtz, Christophe, Lehmann, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566184/
https://www.ncbi.nlm.nih.gov/pubmed/37821965
http://dx.doi.org/10.1186/s13195-023-01318-2