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Benchmarking single-cell hashtag oligo demultiplexing methods

Sample multiplexing is often used to reduce cost and limit batch effects in single-cell RNA sequencing (scRNA-seq) experiments. A commonly used multiplexing technique involves tagging cells prior to pooling with a hashtag oligo (HTO) that can be sequenced along with the cells’ RNA to determine their...

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Detalles Bibliográficos
Autores principales: Howitt, George, Feng, Yuzhou, Tobar, Lucas, Vassiliadis, Dane, Hickey, Peter, Dawson, Mark A, Ranganathan, Sarath, Shanthikumar, Shivanthan, Neeland, Melanie, Maksimovic, Jovana, Oshlack, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566318/
https://www.ncbi.nlm.nih.gov/pubmed/37829177
http://dx.doi.org/10.1093/nargab/lqad086