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Matrix density regulates adipocyte phenotype

Alterations of the extracellular matrix contribute to adipose tissue dysfunction in metabolic disease. We studied the role of matrix density in regulating human adipocyte phenotype in a tunable hydrogel culture system. Lipid accumulation was maximal in intermediate hydrogel density of 5 weight %, re...

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Detalles Bibliográficos
Autores principales: Ky, Alexander, McCoy, Atticus J., Flesher, Carmen G., Friend, Nicole E., Li, Jie, Akinleye, Kore, Patsalis, Christopher, Lumeng, Carey N., Putnam, Andrew J., O’Rourke, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566443/
https://www.ncbi.nlm.nih.gov/pubmed/37815174
http://dx.doi.org/10.1080/21623945.2023.2268261