Photo-caged 2-butene-1,4-dial as an efficient, target-specific photo-crosslinker for covalent trapping of DNA-binding proteins

Covalent trapping of DNA-binding proteins via photo-crosslinking is an advantageous method for studying DNA–protein interactions. However, traditional photo-crosslinkers generate highly reactive intermediates that rapidly and non-selectively react with nearby functional groups, resulting in low targ...

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Detalles Bibliográficos
Autores principales: Li, Jiahui, Cui, Zenghui, Fan, Chaochao, Zhou, Yifei, Ren, Mengtian, Zhou, Chuanzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566456/
https://www.ncbi.nlm.nih.gov/pubmed/37829010
http://dx.doi.org/10.1039/d3sc03719c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566456/
https://www.ncbi.nlm.nih.gov/pubmed/37829010
http://dx.doi.org/10.1039/d3sc03719c

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