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Photo-caged 2-butene-1,4-dial as an efficient, target-specific photo-crosslinker for covalent trapping of DNA-binding proteins
Covalent trapping of DNA-binding proteins via photo-crosslinking is an advantageous method for studying DNA–protein interactions. However, traditional photo-crosslinkers generate highly reactive intermediates that rapidly and non-selectively react with nearby functional groups, resulting in low targ...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566456/ https://www.ncbi.nlm.nih.gov/pubmed/37829010 http://dx.doi.org/10.1039/d3sc03719c |