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Post-synthetic benzylation of the mRNA 5′ cap via enzymatic cascade reactions

mRNAs are emerging modalities for vaccination and protein replacement therapy. Increasing the amount of protein produced by stabilizing the transcript or enhancing translation without eliciting a strong immune response are major steps towards overcoming the present limitations and improving their th...

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Detalles Bibliográficos
Autores principales: Cornelissen, N. V., Mineikaitė, R., Erguven, M., Muthmann, N., Peters, A., Bartels, A., Rentmeister, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566477/
https://www.ncbi.nlm.nih.gov/pubmed/37829022
http://dx.doi.org/10.1039/d3sc03822j