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Post-synthetic benzylation of the mRNA 5′ cap via enzymatic cascade reactions
mRNAs are emerging modalities for vaccination and protein replacement therapy. Increasing the amount of protein produced by stabilizing the transcript or enhancing translation without eliciting a strong immune response are major steps towards overcoming the present limitations and improving their th...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566477/ https://www.ncbi.nlm.nih.gov/pubmed/37829022 http://dx.doi.org/10.1039/d3sc03822j |