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Engineering of antimicrobial peptide fibrils with feedback degradation of bacterial-secreted enzymes

Proteins and peptides can assemble into functional amyloid fibrils with distinct architectures. These amyloid fibrils can fulfil various biological functions in living organisms, and then be degraded. By incorporating an amyloidogenic segment and enzyme-cleavage segment together, we designed a pepti...

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Detalles Bibliográficos
Autores principales: Wang, Fenghua, Xia, Wencheng, Zhang, Mingming, Wu, Rongrong, Song, Xiaolu, Hao, Yun, Feng, Yonghai, Zhang, Liwei, Li, Dan, Kang, Wenyan, Liu, Cong, Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566480/
https://www.ncbi.nlm.nih.gov/pubmed/37829030
http://dx.doi.org/10.1039/d3sc01089a