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Ligand entry pathways control the chemical space recognized by GPR183

The G protein-coupled receptor GPR183 is a chemotactic receptor with an important function in the immune system and association with a variety of diseases. It recognizes ligands with diverse physicochemical properties as both the endogenous oxysterol ligand 7α,25-OHC and synthetic molecules can acti...

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Detalles Bibliográficos
Autores principales: Kjær, Viktoria Madeline Skovgaard, Stępniewski, Tomasz Maciej, Medel-Lacruz, Brian, Reinmuth, Lisa, Ciba, Marija, Rexen Ulven, Elisabeth, Bonomi, Massimiliano, Selent, Jana, Rosenkilde, Mette Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566501/
https://www.ncbi.nlm.nih.gov/pubmed/37829039
http://dx.doi.org/10.1039/d2sc05962b