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Spatiotemporal Regulation of De Novo and Salvage Purine Synthesis during Brain Development
The levels of purines, essential molecules to sustain eukaryotic cell homeostasis, are regulated by the coordination of the de novo and salvage synthesis pathways. In the embryonic central nervous system (CNS), the de novo pathway is considered crucial to meet the requirements for the active prolife...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566546/ https://www.ncbi.nlm.nih.gov/pubmed/37770184 http://dx.doi.org/10.1523/ENEURO.0159-23.2023 |