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Spatiotemporal Regulation of De Novo and Salvage Purine Synthesis during Brain Development

The levels of purines, essential molecules to sustain eukaryotic cell homeostasis, are regulated by the coordination of the de novo and salvage synthesis pathways. In the embryonic central nervous system (CNS), the de novo pathway is considered crucial to meet the requirements for the active prolife...

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Detalles Bibliográficos
Autores principales: Mizukoshi, Tomoya, Yamada, Seiya, Sakakibara, Shin-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566546/
https://www.ncbi.nlm.nih.gov/pubmed/37770184
http://dx.doi.org/10.1523/ENEURO.0159-23.2023