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T-cell redirecting bispecific and trispecific antibodies in multiple myeloma beyond BCMA

PURPOSE OF REVIEW: B-cell maturation antigen (BCMA)-directed T-cell immunotherapies, such as chimeric antigen receptor T-cells (CAR T-cells) and bispecific antibodies (BsAbs) have markedly improved the survival of triple-class refractory multiple myeloma (MM). However, the majority of patients still...

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Detalles Bibliográficos
Autores principales: van de Donk, Niels W.C.J., O’Neill, Chloe, de Ruijter, Maaike E.M., Verkleij, Christie P.M., Zweegman, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566598/
https://www.ncbi.nlm.nih.gov/pubmed/37501530
http://dx.doi.org/10.1097/CCO.0000000000000983