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Opposing action of the FLR-2 glycoprotein hormone and DRL-1/FLR-4 MAP kinases balance p38-mediated growth and lipid homeostasis in C. elegans

Animals integrate developmental and nutritional signals before committing crucial resources to growth and reproduction; however, the pathways that perceive and respond to these inputs remain poorly understood. Here, we demonstrate that DRL-1 and FLR-4, which share similarity with mammalian mitogen-a...

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Detalles Bibliográficos
Autores principales: Torzone, Sarah K., Park, Aaron Y., Breen, Peter C., Cohen, Natalie R., Dowen, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566725/
https://www.ncbi.nlm.nih.gov/pubmed/37773960
http://dx.doi.org/10.1371/journal.pbio.3002320