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Exaggerated elastin turnover in young individuals with Marfan syndrome: new insights from the AIMS trial
AIMS: The fragmentation and loss of elastic fibre in the tunica media of the aorta are pathological hallmarks of Marfan syndrome (MFS) but the dynamics of elastin degradation and its relationship to aortic size and physiological growth remain poorly understood. METHODS AND RESULTS: In this post hoc...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567063/ https://www.ncbi.nlm.nih.gov/pubmed/37829559 http://dx.doi.org/10.1093/ehjopen/oead095 |