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Exaggerated elastin turnover in young individuals with Marfan syndrome: new insights from the AIMS trial

AIMS: The fragmentation and loss of elastic fibre in the tunica media of the aorta are pathological hallmarks of Marfan syndrome (MFS) but the dynamics of elastin degradation and its relationship to aortic size and physiological growth remain poorly understood. METHODS AND RESULTS: In this post hoc...

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Detalles Bibliográficos
Autores principales:	Iskandar, Zaid, Dodd, Matthew, Huang, Jeffrey, Chin, Calvin W L, Stuart, Graham, Caputo, Massimo, Clayton, Tim, Child, Anne, Jin, Xu Yu, Aragon-Martin, José Antonio, Gibb, Jack, Flather, Marcus, Choy, Anna-Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567063/ https://www.ncbi.nlm.nih.gov/pubmed/37829559 http://dx.doi.org/10.1093/ehjopen/oead095

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