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Food and bile micelle binding of quaternary ammonium compounds
BACKGROUND AND PURPOSE: Physiologically-based biopharmaceutics modeling (PBBM) has been widely used to predict the oral absorption of drugs. However, the prediction of food effects on oral drug absorption is still challenging, especially for negative food effects. Marked negative food effects have b...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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International Association of Physical Chemists
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567067/ https://www.ncbi.nlm.nih.gov/pubmed/37829320 http://dx.doi.org/10.5599/admet.2023 |