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DMRT1 regulates human germline commitment

Germline commitment following primordial germ cell (PGC) specification during early human development establishes an epigenetic programme and competence for gametogenesis. Here we follow the progression of nascent PGC-like cells derived from human embryonic stem cells in vitro. We show that switchin...

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Detalles Bibliográficos
Autores principales: Irie, Naoko, Lee, Sun-Min, Lorenzi, Valentina, Xu, Haiqi, Chen, Jinfeng, Inoue, Masato, Kobayashi, Toshihiro, Sancho-Serra, Carmen, Drousioti, Elena, Dietmann, Sabine, Vento-Tormo, Roser, Song, Chun-Xiao, Surani, M. Azim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567552/
https://www.ncbi.nlm.nih.gov/pubmed/37709822
http://dx.doi.org/10.1038/s41556-023-01224-7