Cargando…
DMRT1 regulates human germline commitment
Germline commitment following primordial germ cell (PGC) specification during early human development establishes an epigenetic programme and competence for gametogenesis. Here we follow the progression of nascent PGC-like cells derived from human embryonic stem cells in vitro. We show that switchin...
Autores principales: | Irie, Naoko, Lee, Sun-Min, Lorenzi, Valentina, Xu, Haiqi, Chen, Jinfeng, Inoue, Masato, Kobayashi, Toshihiro, Sancho-Serra, Carmen, Drousioti, Elena, Dietmann, Sabine, Vento-Tormo, Roser, Song, Chun-Xiao, Surani, M. Azim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567552/ https://www.ncbi.nlm.nih.gov/pubmed/37709822 http://dx.doi.org/10.1038/s41556-023-01224-7 |
Ejemplares similares
-
A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development
por: Tang, Walfred W.C., et al.
Publicado: (2015) -
Regulation of pluripotency in male germline stem cells by Dmrt1
por: Takashima, Seiji, et al.
Publicado: (2013) -
Activation of Lineage Regulators and Transposable Elements across a Pluripotent Spectrum
por: Hackett, Jamie A., et al.
Publicado: (2017) -
Conserved features of non-primate bilaminar disc embryos and the germline
por: Alberio, Ramiro, et al.
Publicado: (2021) -
SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate
por: Irie, Naoko, et al.
Publicado: (2015)