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Inactivation of the Kv2.1 channel through electromechanical coupling

The Kv2.1 voltage-activated potassium (Kv) channel is a prominent delayed-rectifier Kv channel in the mammalian central nervous system, where its mechanisms of activation and inactivation are critical for regulating intrinsic neuronal excitability(1,2). Here we present structures of the Kv2.1 channe...

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Detalles Bibliográficos
Autores principales: Fernández-Mariño, Ana I., Tan, Xiao-Feng, Bae, Chanhyung, Huffer, Kate, Jiang, Jiansen, Swartz, Kenton J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567553/
https://www.ncbi.nlm.nih.gov/pubmed/37758949
http://dx.doi.org/10.1038/s41586-023-06582-8