Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment

The assembly of cortical circuits involves the generation and migration of interneurons from the ventral to the dorsal forebrain(1–3), which has been challenging to study at inaccessible stages of late gestation and early postnatal human development(4). Autism spectrum disorder and other neurodevelo...

Descripción completa

Detalles Bibliográficos
Autores principales: Meng, Xiangling, Yao, David, Imaizumi, Kent, Chen, Xiaoyu, Kelley, Kevin W., Reis, Noah, Thete, Mayuri Vijay, Arjun McKinney, Arpana, Kulkarni, Shravanti, Panagiotakos, Georgia, Bassik, Michael C., Pașca, Sergiu P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567561/
https://www.ncbi.nlm.nih.gov/pubmed/37758944
http://dx.doi.org/10.1038/s41586-023-06564-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567561/
https://www.ncbi.nlm.nih.gov/pubmed/37758944
http://dx.doi.org/10.1038/s41586-023-06564-w

Ejemplares similares