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Au@(109)Pd core–shell nanoparticle conjugated to trastuzumab for the therapy of HER2+ cancers: studies on the applicability of (109)Pd/(109m)Ag in vivo generator in combined β(−) auger electron therapy

BACKGROUND: In radionuclide therapy, to enhance therapeutic efficacy, an intriguing alternative is to ensure the simultaneous implementation of low- and high-LET radiation emitted from a one radionuclide. In the present study, we introduce the concept of utilizing (109)Pd (T(1/2) = 13.7 h) in the fo...

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Detalles Bibliográficos
Autores principales: Gharibkandi, Nasrin Abbasi, Wawrowicz, Kamil, Majkowska-Pilip, Agnieszka, Żelechowska-Matysiak, Kinga, Wierzbicki, Mateusz, Bilewicz, Aleksander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567614/
https://www.ncbi.nlm.nih.gov/pubmed/37821747
http://dx.doi.org/10.1186/s41181-023-00212-4