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Increased acylcarnitines in infant heart failure indicate fatty acid oxidation inhibition: towards therapeutic options?

AIMS: Heart failure in adults is characterized by reduction of long‐chain fatty acid oxidation in favour of carbohydrate metabolism. This adaptive phenomenon becomes maladaptive because energy conversion decreases and lipid toxic derivatives known to impair cardiac function are accumulating. No data...

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Detalles Bibliográficos
Autores principales: Issa, Jean, Lodewyckx, Pierre, Blasco, Hélène, Benz‐de‐Bretagne, Isabelle, Labarthe, François, Lefort, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567663/
https://www.ncbi.nlm.nih.gov/pubmed/37614055
http://dx.doi.org/10.1002/ehf2.14449