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Revealing invisible cell phenotypes with conditional generative modeling

Biological sciences, drug discovery and medicine rely heavily on cell phenotype perturbation and microscope observation. However, most cellular phenotypic changes are subtle and thus hidden from us by natural cell variability: two cells in the same condition already look different. In this study, we...

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Detalles Bibliográficos
Autores principales: Lamiable, Alexis, Champetier, Tiphaine, Leonardi, Francesco, Cohen, Ethan, Sommer, Peter, Hardy, David, Argy, Nicolas, Massougbodji, Achille, Del Nery, Elaine, Cottrell, Gilles, Kwon, Yong-Jun, Genovesio, Auguste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567685/
https://www.ncbi.nlm.nih.gov/pubmed/37821450
http://dx.doi.org/10.1038/s41467-023-42124-6