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Tripartite motif containing 26 prevents steatohepatitis progression by suppressing C/EBPδ signalling activation

Currently potential preclinical drugs for the treatment of nonalcoholic steatohepatitis (NASH) and NASH-related pathopoiesis have failed to achieve expected therapeutic efficacy due to the complexity of the pathogenic mechanisms. Here we show Tripartite motif containing 26 (TRIM26) as a critical end...

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Detalles Bibliográficos
Autores principales: Xu, Minxuan, Tan, Jun, Liu, Xin, Han, Li, Ge, Chenxu, Zhang, Yujie, Luo, Fufang, Wang, Zhongqin, Xue, Xiaoqin, Xiong, Liangyin, Wang, Xin, Zhang, Qinqin, Wang, Xiaoxin, Tian, Qin, Zhang, Shuguang, Meng, Qingkun, Dai, Xianling, Kuang, Qin, Li, Qiang, Lou, Deshuai, Hu, Linfeng, Liu, Xi, Kuang, Gang, Luo, Jing, Chang, Chunxiao, Wang, Bochu, Chai, Jie, Shi, Shengbin, Han, Lianyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567751/
https://www.ncbi.nlm.nih.gov/pubmed/37821436
http://dx.doi.org/10.1038/s41467-023-42040-9