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The effect of random virus failure following cell entry on infection outcome and the success of antiviral therapy

A virus infection can be initiated with very few or even a single infectious virion, and as such can become extinct, i.e. stochastically fail to take hold or spread significantly. There are many ways that a fully competent infectious virion, having successfully entered a cell, can fail to cause a pr...

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Detalles Bibliográficos
Autores principales: Quirouette, Christian, Cresta, Daniel, Li, Jizhou, Wilkie, Kathleen P., Liang, Haozhao, Beauchemin, Catherine A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567758/
https://www.ncbi.nlm.nih.gov/pubmed/37821517
http://dx.doi.org/10.1038/s41598-023-44180-w