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NARFL deficiency caused mitochondrial dysfunction in lung cancer cells by HIF-1α–DNMT1 axis

NARFL was reported to be a component of cytosolic iron–sulfur cluster assembly pathway and a causative gene of the diffused pulmonary arteriovenous malformations (dPAVMs). NARFL knockout dramatically impaired mitochondrial integrity in mice, which might promote mitochondrial dysfunction and lead to...

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Detalles Bibliográficos
Autores principales: Liu, Hongzhou, Wu, Xueqin, Yang, Tianrong, Wang, Chen, Huang, Fei, Xu, Ying, Peng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567771/
https://www.ncbi.nlm.nih.gov/pubmed/37821486
http://dx.doi.org/10.1038/s41598-023-44418-7