The role of inflammation and antioxidant defenses in the cardiotoxicity of doxorubicin in elderly CD-1 male mice

Doxorubicin (DOX) is a potent chemotherapeutic agent used against several cancer types. However, due to its cardiotoxic adverse effects, the use of this drug may be also life-threatening. Although most cancer patients are elderly, they are poorly represented and evaluated in pre-clinical and clinica...

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Detalles Bibliográficos
Autores principales: Reis-Mendes, Ana, Ferreira, Mariana, Duarte, José Alberto, Duarte-Araújo, Margarida, Remião, Fernando, Carvalho, Félix, Sousa, Emília, Bastos, Maria Lourdes, Costa, Vera Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Organ Toxicity and Mechanisms
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567829/
https://www.ncbi.nlm.nih.gov/pubmed/37676301
http://dx.doi.org/10.1007/s00204-023-03586-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567829/
https://www.ncbi.nlm.nih.gov/pubmed/37676301
http://dx.doi.org/10.1007/s00204-023-03586-1

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