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Aqueous Nyctanthes arbortristis and doxorubicin conjugated gold nanoparticles synergistically induced mTOR-dependent autophagy-mediated ferritinophagy in paclitaxel-resistant breast cancer stem cells

Aim: Nyctanthes arbortristis Linn is a potential anti-diabetic drug that reduces glucose levels by delaying carbohydrate digestion. The tumor microenvironment is characterized by elevated glucose levels that activate various genes, such as mTOR. mTOR plays a critical role in maintaining the hypoxic...

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Detalles Bibliográficos
Autores principales: Chittineedi, Prasanthi, Pandrangi, Santhi Latha, Neira Mosquera, Juan Alejandro, Sánchez Llaguno, Sungey Naynee, Mohiddin, Gooty Jaffer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568009/
https://www.ncbi.nlm.nih.gov/pubmed/37841922
http://dx.doi.org/10.3389/fphar.2023.1201319