OffRisk: a docker image for annotating CRISPR off-target sites in the human genome

SUMMARY: The CRISPR-Cas9 system has been adapted to achieve targeted genome editing as well as transcriptional control by customizing 20-nt guide RNA (gRNA) molecules for desired regions in the target genome. Designing gRNAs must consider nonspecific and unintended binding, known as off-targets, sin...

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Detalles Bibliográficos
Autores principales: Barkai, Gil-ad, Malul, Tal, Eliaz, Yossi, Eyal, Eran, Veksler-Lublinsky, Isana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Application Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568243/
https://www.ncbi.nlm.nih.gov/pubmed/37840905
http://dx.doi.org/10.1093/bioadv/vbad138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568243/
https://www.ncbi.nlm.nih.gov/pubmed/37840905
http://dx.doi.org/10.1093/bioadv/vbad138

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