Cargando…

Loss of INPP5K attenuates IP(3)-induced Ca(2+) responses in the glioblastoma cell line U-251 MG cells

INPP5K (inositol polyphosphate 5-phosphatase K) is an endoplasmic reticulum (ER)-resident enzyme that acts as a phosphoinositide (PI) 5-phosphatase, capable of dephosphorylating various PIs including PI 4,5-bisphosphate (PI(4,5)P(2)), a key phosphoinositide found in the plasma membrane. Given its ER...

Descripción completa

Detalles Bibliográficos
Autores principales: Loncke, Jens, Luyten, Tomas, Ramos, Ana Raquel, Erneux, Christophe, Bultynck, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568277/
https://www.ncbi.nlm.nih.gov/pubmed/37842182
http://dx.doi.org/10.1016/j.bbadva.2023.100105