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Universal ddPCR-based assay for the determination of lentivirus infectious titer and lenti-modified cell vector copy number

The translation of cell-based therapies from research to clinical setting requires robust analytical methods that successfully adhere to current good manufacturing practices and regulatory guidelines. Lentiviral vectors are commonly used for gene delivery to generate genetically modified therapeutic...

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Detalles Bibliográficos
Autores principales: Kandell, Jennifer, Milian, Steven, Snyder, Richard, Lakshmipathy, Uma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568280/
https://www.ncbi.nlm.nih.gov/pubmed/37841416
http://dx.doi.org/10.1016/j.omtm.2023.101120