A microbiological system for screening the interference of XNA monomers with DNA and RNA metabolism

We explored the toxicity and mutagenicity of a wide range of xenobiotic nucleoside triphosphates to an Escherichia coli strain equipped with a nucleoside triphosphate transporter. This bacterial test provides a tool to evaluate and guide the synthesis of nucleotides for applications such as the prop...

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Detalles Bibliográficos
Autores principales: Blanchard, Aude, Abramov, Mikhail, Hassan, Camille, Marlière, Philippe, Herdewijn, Piet, Pezo, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568403/
https://www.ncbi.nlm.nih.gov/pubmed/37842681
http://dx.doi.org/10.1039/d3ra06172h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568403/
https://www.ncbi.nlm.nih.gov/pubmed/37842681
http://dx.doi.org/10.1039/d3ra06172h

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