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B cell diversification in gut-associated lymphoid tissues: From birds to humans

Several species generate their preimmune repertoire in gut-associated lymphoid tissues (GALT), compensating a reduced germline V gene repertoire by post-rearrangement diversification mechanisms (gene conversion and/or somatic hypermutation) in these environments that act as primary lymphoid organs....

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Detalles Bibliográficos
Autores principales: Weill, Jean-Claude, Weller, Sandra, Reynaud, Claude-Agnès
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568490/
https://www.ncbi.nlm.nih.gov/pubmed/37824081
http://dx.doi.org/10.1084/jem.20231501