High expression of P-selectin induces neutrophil extracellular traps via the PSGL-1/Syk/Ca(2+)/PAD4 pathway to exacerbate acute pancreatitis

BACKGROUND: Excessive neutrophil extracellular traps (NETs) is involved in the progression of acute pancreatitis (AP) but the mechanisms controlling NETs formation in AP are not fully understood. Therefore, our study sought to investigate the mechanism of the highly expressed P-selectin stimulating...

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Detalles Bibliográficos
Autores principales: Xu, Qi, Shi, Ming, Ding, Lu, Xia, Yu, Luo, Liang, Lu, Xiaofang, Zhang, Xiaoying, Deng, David Y. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568494/
https://www.ncbi.nlm.nih.gov/pubmed/37841279
http://dx.doi.org/10.3389/fimmu.2023.1265344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568494/
https://www.ncbi.nlm.nih.gov/pubmed/37841279
http://dx.doi.org/10.3389/fimmu.2023.1265344

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