Cryogenic Soft Landing Improves Structural Preservation of Protein Complexes

[Image: see text] We describe an apparatus for the cryogenic landing of particles from the ion beam of a mass spectrometer onto transmission electron microscope grids for cryo-electron microscopy. This system also allows for the controlled formation of thin films of amorphous ice on the grid surface...

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Detalles Bibliográficos
Autores principales: Westphall, Michael S., Lee, Kenneth W., Hemme, Colin, Salome, Austin Z., Mertz, Keaton, Grant, Timothy, Coon, Joshua J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568529/
https://www.ncbi.nlm.nih.gov/pubmed/37732836
http://dx.doi.org/10.1021/acs.analchem.3c03228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568529/
https://www.ncbi.nlm.nih.gov/pubmed/37732836
http://dx.doi.org/10.1021/acs.analchem.3c03228

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