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Cryogenic Soft Landing Improves Structural Preservation of Protein Complexes
[Image: see text] We describe an apparatus for the cryogenic landing of particles from the ion beam of a mass spectrometer onto transmission electron microscope grids for cryo-electron microscopy. This system also allows for the controlled formation of thin films of amorphous ice on the grid surface...
Autores principales: | Westphall, Michael S., Lee, Kenneth W., Hemme, Colin, Salome, Austin Z., Mertz, Keaton, Grant, Timothy, Coon, Joshua J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568529/ https://www.ncbi.nlm.nih.gov/pubmed/37732836 http://dx.doi.org/10.1021/acs.analchem.3c03228 |
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