Resveratrol inhibits ferroptosis and decelerates heart failure progression via Sirt1/p53 pathway activation

Resveratrol is an organic compound widely studied for its therapeutic uses. We investigated whether resveratrol exerts cardioprotective effects by inhibiting ferroptosis via the Sirt1/p53 pathway. A heart failure model was established by aortic coarctation in Sirt1 knockout mice. The superoxide dism...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Qian, Shaohuan, Tang, Bi, Kang, Pinfang, Zhang, Heng, Shi, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568670/
https://www.ncbi.nlm.nih.gov/pubmed/37487007
http://dx.doi.org/10.1111/jcmm.17874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568670/
https://www.ncbi.nlm.nih.gov/pubmed/37487007
http://dx.doi.org/10.1111/jcmm.17874

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