Summary-data based Mendelian randomization identifies gene expression regulatory polymorphisms associated with bovine paratuberculosis by modulation of the nuclear factor Kappa β (NF-κß)-mediated inflammatory response

Genome-wide association studies (GWAS) have identified host genetic variants associated with paratuberculosis (PTB) susceptibility. Most of the GWAS-identified SNPs are in non-coding regions. Connecting these non-coding variants and downstream affected genes is a challenge and, up to date, only a fe...

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Detalles Bibliográficos
Autores principales: Badia-Bringué, Gerard, Canive, Maria, Fernandez-Jimenez, Nora, Lavín, José Luis, Casais, Rosa, Blanco-Vázquez, Cristina, Vázquez, Patricia, Fernández, Almudena, Bilbao, Jose Ramón, Garrido, Joseba M., Juste, Ramón A., González-Recio, Oscar, Alonso-Hearn, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568764/
https://www.ncbi.nlm.nih.gov/pubmed/37821814
http://dx.doi.org/10.1186/s12864-023-09710-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568764/
https://www.ncbi.nlm.nih.gov/pubmed/37821814
http://dx.doi.org/10.1186/s12864-023-09710-w

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