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Summary-data based Mendelian randomization identifies gene expression regulatory polymorphisms associated with bovine paratuberculosis by modulation of the nuclear factor Kappa β (NF-κß)-mediated inflammatory response
Genome-wide association studies (GWAS) have identified host genetic variants associated with paratuberculosis (PTB) susceptibility. Most of the GWAS-identified SNPs are in non-coding regions. Connecting these non-coding variants and downstream affected genes is a challenge and, up to date, only a fe...
Autores principales: | Badia-Bringué, Gerard, Canive, Maria, Fernandez-Jimenez, Nora, Lavín, José Luis, Casais, Rosa, Blanco-Vázquez, Cristina, Vázquez, Patricia, Fernández, Almudena, Bilbao, Jose Ramón, Garrido, Joseba M., Juste, Ramón A., González-Recio, Oscar, Alonso-Hearn, Marta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568764/ https://www.ncbi.nlm.nih.gov/pubmed/37821814 http://dx.doi.org/10.1186/s12864-023-09710-w |
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