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OCOSO2: study protocol for a single-blinded, multicentre, randomised controlled trial assessing a central venous oxygen saturation-based goal-directed therapy to reduce postoperative complications in high-risk patients after elective major surgery

BACKGROUND: Fluid loading-based goal-directed therapy is a cornerstone of anaesthesia management in major surgery. Its widespread application has contributed to a significant improvement in perioperative morbidity and mortality. In theory, only hypovolemic patients should receive fluid therapy. Howe...

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Detalles Bibliográficos
Autores principales: Pastene, Bruno, Bernat, Matthieu, Baumstark, Karine, Bezulier, Karine, Gricourt, Yann, De Guibert, Jean-Manuel, Charvet, Aude, Colin, Manon, Leone, Marc, Zieleskiewicz, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568773/
https://www.ncbi.nlm.nih.gov/pubmed/37821968
http://dx.doi.org/10.1186/s13063-023-07689-z