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OCOSO2: study protocol for a single-blinded, multicentre, randomised controlled trial assessing a central venous oxygen saturation-based goal-directed therapy to reduce postoperative complications in high-risk patients after elective major surgery
BACKGROUND: Fluid loading-based goal-directed therapy is a cornerstone of anaesthesia management in major surgery. Its widespread application has contributed to a significant improvement in perioperative morbidity and mortality. In theory, only hypovolemic patients should receive fluid therapy. Howe...
Autores principales: | Pastene, Bruno, Bernat, Matthieu, Baumstark, Karine, Bezulier, Karine, Gricourt, Yann, De Guibert, Jean-Manuel, Charvet, Aude, Colin, Manon, Leone, Marc, Zieleskiewicz, Laurent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568773/ https://www.ncbi.nlm.nih.gov/pubmed/37821968 http://dx.doi.org/10.1186/s13063-023-07689-z |
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