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Caspase 6 promotes innate immune activation by functional crosstalk between RIPK1-IκBα axis in liver inflammation

BACKGROUND: Caspase 6 is an essential regulator in innate immunity, inflammasome activation and host defense. We aimed to characterize the causal mechanism of Caspase 6 in liver sterile inflammatory injury. METHODS: Human liver tissues were harvested from patients undergoing ischemia-related hepatec...

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Detalles Bibliográficos
Autores principales: Lin, Yuanbang, Sheng, Mingwei, Qin, Hua, Zhang, Peng, Wang, Chunli, Fu, Wei, Meng, Xiangjun, Wang, Duowei, Hou, Yachao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568785/
https://www.ncbi.nlm.nih.gov/pubmed/37828624
http://dx.doi.org/10.1186/s12964-023-01287-x