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Caspase 6 promotes innate immune activation by functional crosstalk between RIPK1-IκBα axis in liver inflammation

BACKGROUND: Caspase 6 is an essential regulator in innate immunity, inflammasome activation and host defense. We aimed to characterize the causal mechanism of Caspase 6 in liver sterile inflammatory injury. METHODS: Human liver tissues were harvested from patients undergoing ischemia-related hepatec...

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Detalles Bibliográficos
Autores principales:	Lin, Yuanbang, Sheng, Mingwei, Qin, Hua, Zhang, Peng, Wang, Chunli, Fu, Wei, Meng, Xiangjun, Wang, Duowei, Hou, Yachao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568785/ https://www.ncbi.nlm.nih.gov/pubmed/37828624 http://dx.doi.org/10.1186/s12964-023-01287-x

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