Cargando…
Global analysis of suppressor mutations that rescue human genetic defects
BACKGROUND: Genetic suppression occurs when the deleterious effects of a primary “query” mutation, such as a disease-causing mutation, are rescued by a suppressor mutation elsewhere in the genome. METHODS: To capture existing knowledge on suppression relationships between human genes, we examined 2,...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568808/ https://www.ncbi.nlm.nih.gov/pubmed/37821946 http://dx.doi.org/10.1186/s13073-023-01232-0 |