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The prevalence of lynch syndrome (DNA mismatch repair protein deficiency) in patients with primary localized prostate cancer using immunohistochemistry screening

BACKGROUND: Prostate cancer is one of the most heritable human cancers. Lynch syndrome is an autosomal dominant inheritance caused by germline mutations in DNA mismatch repair (MMR) genes, which are also associated with an increased incidence of prostate cancer. However, prostate cancer has not been...

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Detalles Bibliográficos
Autores principales: Oka, Suguru, Urakami, Shinji, Hagiwara, Kiichi, Hayashida, Michikata, Sakaguchi, Kazushige, Miura, Yuji, Inoshita, Naoko, Arai, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568829/
https://www.ncbi.nlm.nih.gov/pubmed/37828628
http://dx.doi.org/10.1186/s13053-023-00265-1